Ongoing Trials


About Our Trials


New clinical trials start up continually throughout the year as Contract Research Organizations reach out to Quality of Life Research to consider and undertake new studies. Following is a list of studies that are currently enrolling. If you think you might be interested in participating, follow this link to express interest and we will contact you with more information and to determine if you qualify.

One Time Blood Draw


Quality of Life Research is recruiting patients who might be considered to be at high risk for developing lung cancer.

To qualify, patients should be at least 50 years of age and have a history of smoking one pack of cigarettes per day, either currently or in the past.

Individuals with a history of blood transfusions or hematologic malignancies are excluded.

Patients will receive $50 for their time and travel.

HPV Specimen Collection Study

Women Undergoing Routine Cervical Cancer Screening


Inclusion:

  • Is 25 years of age or older
  • Is attending a participating clinic for routine cervical cancer screening following screening guidelines
  • Has an intact cervix
  • Is willing and able to provide documented informed consent
  • Is willing and able to undergo colposcopy, biopsy, and endocervical curettage (ECC) within 12 weeks (≤ 84 days) from the baseline visit, if required
  • Is willing and able to allow collection of two cervical cytology specimens

Exclusion:

  • Is pregnant at the time of visit or plans to become pregnant within the following 12 weeks
  • Has any known medical condition that, in the opinion of the investigator, would result in increased bleeding from biopsy
  • Has a known history of excisional or ablative therapy (e.g., LEEP, cone biopsy, cervical laser surgery, or cryotherapy) to the cervix in the last 12 months prior to the baseline visit
  • Had a cervical cytology specimen collected within the last 4 months
  • Is currently participating in any diagnostic trial for cervical cancer
  • Had a complete or partial hysterectomy, either supra cervical or involving removal of the cervix
  • Is currently participating or planning to participate in any clinical trial for HPV treatment (for the duration of this study)
  • Previous participation in this study

HPV Specimen Collection Study

Women Referred to Colposcopy


Inclusion:

  • Is willing and able to provide documented informed consent (or her legal representative is willing and able)
  • Is 25 years of age or older
  • Has had a colposcopy referral in which routine cervical cancer screening has included HR HPV testing (HPV primary screening, co-testing, or ASC-US cytology triage) performed within 12 weeks preceding the colposcopy visit
  • Has an intact cervix
  • Is willing and able to undergo colposcopy, biopsy, and endocervical curettage (ECC)
  • Is willing and able to allow collection of two cervical cytology specimens

Exclusion:

  • Is pregnant when presenting for colposcopy
  • Has any known medical condition that, in the opinion of the investigator, would result in increased risk of bleeding at biopsy
  • Has a known history of excisional or ablative therapy (eg, LEEP, cone biopsy, cervical laser surgery, or cryotherapy) to the cervix in the last 12 months prior to the colposcopy visit
  • Is currently participating in any diagnostic trial for cervical cancer
  • Had a complete or partial hysterectomy, either supracervical or involving removal of the cervix
  • Is currently participating or planning to participate in any clinical trial for HPV treatment (for the duration of this study)
  • Is referred to colposcopy based on a cytology-only screening program
  • HR HPV referral test is known to be the Roche cobas® HPV test
  • Previous participation in this study

Male Hormone Replacement

Of Long-term Vascular Events and efficacy Response in hypogonadal men


Inclusion:

  • Men whose age is between 45-80 years, inclusive, at the time of screening
  • Two serum testosterone levels < 300
  • Pre-existing Cardiovascular disease
  • Decreased sexual desire or libido
  • Decreased spontaneous erections
  • Decreased energy or fatigue/feeling tired
  • Low mood or depressed mood
  • Loss of body hair or reduced shaving
  • Hot Flashes

Exclusion:

  • Congenital or acquired hypogandism for whom long-term therapy with placebo would not be medically appropriate
  • Two testosterone levels < 100 during screening
  • Current or recurrent ulcer, erosion, lichenification, inflammation psoriasis, eczema or use of topical cortiosterioids on the upper arm and shoulders
  • Known skin intolerance to alocohol or allergy to any of the ingredients of the study drug (AndroGel 1.62% prescribing information)
  • History of treatment with growth hormone last 90 days
  • Subject taking high dose of opoids
  • History of prostate cancer
  • Severe lower urinary tract symptoms
  • Prostate nodule
  • PSA > 3.0
FAQ
How do clinical trials work?
Clinical trials are a core part of the medical research process. They allow scientists to test whether new treatments, drugs and practices will work before they try them out on patients in real life settings. Clinical trials often have strict guidelines for participation because participants must be healthy adults who meet certain criteria or suffer from specific conditions; additionally, clinical trial subjects may agree to participate in studies that are paid compensation but do not provide any other form of payment outside of their involvement with the study itself (such as through insurance).
Why are clinical trials randomized?
At several points during and at the end of the clinical trial, researchers compare the groups to see which treatment is more effective or has fewer side effects. Randomization helps prevent bias. Bias occurs when a trial’s results are affected by human choices or other factors not related to the treatment being tested.
Can clinical trials cure cancer?
Sadly, most commercially available treatments cannot cure cancer; clinical trials offer hope that we can improve outcomes for individual patients in the near or distant future by collecting information from different populations around the world to develop effective treatment methods based on what’s working with those who have similar diagnoses as well as why they’re not responding to specific drugs like others do.